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Highlights from April 2015 UOG: an Editorial on the use of whole genome array in prenatal screening; a systematic review on the management of ovarian hyperstimulation syndrome; an original article from Kypros Nicolaides' group on prediction of adverse perinatal outcomes and the use of ultrasound in assessment cervical cancer.

ISUOG News: 02 April 2015

The April issue of Ultrasound in Obstetrics & Gynecology contains 12 original articles including the following open-access features:

The advantages of whole genome array as a first-tier diagnostic prenatal test

An Editorial by Malgorzata I. Srebniak et al. advocates the use of whole genome array testing for routine prenatal cytogenetic diagnoses, demonstrating that the advantages of the procedure outweigh the disadvantages. The overview, however, is written with caution, highlighting the need for a policy concerning what to report specifically and the protocols to follow when offering patients a choice on the predetermined outcomes about which they wish to be informed.

View the full article

Managing ovarian hyperstimulation syndrome whilst achieving high pregnancy rates

Two combined systematic reviews and meta-analyses by Carolina Nastri et al. evaluated studies examining methods of predicting ovarian hyperstimulation syndrome (OHSS) and high ovarian response to controlled ovarian stimulation. The study aimed to estimate the effect of interventions to reduce the risk of high ovarian response and/or occurrence of OHSS without jeopardizing pregnancy rates.

View the full article

Cerebroplacental ratio at 30–34 weeks’ provides poor detection rates for adverse perinatal outcomes

An original article from Kypros Nicolaides’ group; one of two published in this month’s issue, investigated the potential value of using cerebroplacental ratio (CPR) at 30–34 weeks’ gestation when screening for adverse perinatal outcomes. The study screened 30 780 singleton pregnancies at 30–34 weeks’ gestation and found that the performance of measuring CPR in routine screening for adverse perinatal outcome is poor, detecting only 5–11 % for each outcome.

View the full article

2D and 3D ultrasound should be considered for preoperative work-up for cervical cancer

This month’s Journal Club article by Valentina Chiappa et al. is an original paper comparing the performance of 2D and 3D ultrasound with MRI as the gold standard in the assessment of parametrial infiltration of cervical cancer and to determine if all parts of the cervix are equally assessable by ultrasound. The study found ultrasound assessment of the cervix to be equally as effective and, as ultrasound is less costly and more readily available than MRI, recommend it for consideration in preoperative work-up for cervical cancer.

View the Journal Club slides and the full article.


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