The June issue of Ultrasound in Obstetrics & Gynecology contains 13 Original Articles; an Editorial; a Systematic Review; and two Randomized Controlled Trials.
Please see below a selection of articles from the June issue of the Journal chosen specially by the UOG team. To view all UOG content become an ISUOG member today.
Prenatal counseling for neurodevelopmental delay in congenital heart disease
Congenital heart disease (CHD) has been associated with neurodevelopmental delay (NDD) in many studies, however the relationship is poorly understood. Evidence from imaging and clinical studies documenting brain lesions and likely risk of NDD in the fetus with CHD has raised concern among health professionals involved in prenatal counseling, particularly that discussing adverse neurodevelopmental outcomes may lead couples to terminate the pregnancy for isolated CHD associated with low mortality and long-term morbidity. These uncertainties led Paladini et al. to prepare a web-based survey for CHD referral units worldwide, to gather information on healthcare professionals’ practice, their understanding of the evidence base for NDD in CHD and how they convey this information during prenatal counseling. The results of their survey are reported in an Editorial in the new issue of UOG.
View the Editorial here.
This article is only available to subscribers of UOG; remember to login to the ISUOG website to access these articles, or become an ISUOG member to subscribe to UOG.
Single deepest vertical pocket or amniotic fluid index to predict adverse pregnancy outcome
Measurement of amniotic fluid volume is an important method for assessment of fetal health as oligohydramnios occurs in many high-risk conditions and is associated with adverse perinatal outcome. However, the limitations of direct invasive measurement have led to the use of ultrasound for amniotic fluid volume estimation, often by assessment of the amniotic fluid index (AFI) or by the single deepest vertical pocket (SDP) technique. As of yet, there is no clear consensus on which method is best for this assessment. In this randomized controlled trial by Kehl et al., 1052 women were randomized to evaluation of amniotic fluid volume by AFI or by SDP in order to determine which technique is best for predicting adverse pregnancy outcome.
View the full article and accompanying Journal Clubs slides.
Screening for trisomies by cell-free DNA testing
Cell-free DNA analysis of maternal blood is an effective method of screening for fetal trisomies. Two articles in this issue of UOG discuss cell-free DNA testing: Revello et al. describe the rate of a failed test result in pregnancies affected by trisomy compared to the rate in non-affected pregnancies, and discuss the options of further management in those with a failed result; and Sarno et al. (member access only) examine the performance of cell-free DNA testing for fetal trisomies in twin pregnancies, and compare the rate of test failure in twin and singleton pregnancies.