A free-access Special Issue on Reproductive Medicine from Ultrasound in Obstetrics & Gynecology featuring research and systematic reviews from international experts in the field. The entire issue will be accessible in January 2018.


IVF/ICSI treatment increases the risk of spontaneous preterm birth in singleton pregnancies

Meta-analysis of cohort studies shows an increased risk of spontaneous preterm birth at both <37 and <34 weeks’ gestation in pregnancies conceived by IVF/ICSI compared with those conceived spontaneously.

View the press release on this article with a comment from Dr Nick Raine-Fenning.


GnRHa during cancer chemotherapy reduces the risk of primary ovarian insufficiency and increases the rate of spontaneous pregnancy

A meta-analysis of RCTs suggests that use of GnRHa during cancer chemotherapy reduces the risk of primary ovarian insufficiency/amenorrhea and increases the rate of spontaneous pregnancy. These benefits could be demonstrated for patients with breast cancer, not for those with lymphoma.

 

HPV infection in male partners reduces live birth/ongoing pregnancy rate and increases rate of miscarriage in pregnancies undergoing IVF

A meta-analysis of observational studies on women undergoing IVF shows that, whilst the common sexually-transmitted HPV infection in women had no effect on IVF outcomes, HPV infection of their male partners significantly reduced live birth/ongoing pregnancy rate and increased rate of miscarriage.

 

IVF/ICSI pregnancy increases risk of fetal congenital heart defects

A meta-analysis of cohort studies shows that the risk of CHD in IVF/ICSI pregnancies is significantly increased by about 50% as compared with pregnancies conceived spontaneously.

View the press release on this article. 

 

Fetal cardiac remodeling occurs in twin pregnancies conceived following assisted reproductive technology

Prospective cohort study comparing dichorionic twin fetuses conceived by ART and spontaneously conceived twin pregnancies, measuring a range of morphological and functional cardiac parameters, provides evidence of fetal cardiac remodeling and dysfunction in twins conceived by ART.

 

Expert international consensus on how to count ovarian antral follicles by ultrasound

Consensus paper from an international group of clinicians and sonologists summarizing important aspects of the available techniques for counting ovarian follicles, suggesting minimum standards to improve reliability and minimise patient discomfort and proposing a standardized report to describe antral follicle evaluation.

 

Improved criteria for distinguishing between normal/arcuate and septate uterus

A validation study showing a good level of agreement among international experts using the coronal view of the uterus to differentiate septate from normal/arcuate uterus, and poor agreement with ESHRE-ESGE and ASRM criteria, which over- and underestimate, respectively, the prevalence of septate uterus.

 

Misoprostol treatment is more effective than expectant management in women with early miscarriage

A randomized controlled trial shows that in women with early non-viable pregnancy and vaginal bleeding, misoprostol treatment is more effective than is expectant management for complete evacuation of the uterus.

 

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