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The April issue of Ultrasound in Obstetrics & Gynecology includes a systematic review evaluating the safety and effectiveness of prenatal valacyclovir therapy in prevention and treatment of congenital cytomegalovirus infection, a large population-based study investigating the link between birth-weight centile and school performance, a prospective longitudinal study providing reference ranges for uterine artery pulsatility index across gestation and a Delphi consensus study focusing on ultrasound in the prenatal evaluation and management of patients at high risk of placenta accreta spectrum at delivery.

The March issue of Ultrasound in Obstetrics & Gynecology includes a study evaluating the cost-effectiveness of performing an ultrasound assessment before cell-free DNA analysis for fetal aneuploidy screening, a study investigating the impact of prenatal exome sequencing on perinatal outcome, a prospective study assessing the potential of lower uterine segment thickness in identifying women at risk of Cesarean delivery following labor induction, and a systematic review and meta-analysis assessing the diagnostic accuracy of individual ultrasound signs for detecting adnexal torsion.

The February issue of Ultrasound in Obstetrics & Gynecology includes a systematic review and meta-analysis investigating neonatal and long-term outcomes of pregnancies with cytomegalovirus infection and negative amniocentesis, a national cohort study exploring the association of cerebral palsy with placental and umbilical cord disorders, and a systematic review of studies reporting on maternal and perinatal outcomes of pregnancies complicated by poxvirus infections, including monkeypox. Also in the issue are a new study from the IOTA collaboration describing a novel strategy allowing to reliably discriminate between benign and malignant ovarian tumors and an accompanying Editorial on the topic by Prof. Davor Jurkovic. Finally, the February issue includes the newly updated ISUOG Practice Guideline on the performance of fetal magnetic resonance imaging.

The January issue of Ultrasound in Obstetrics & Gynecology includes a systematic review and meta-analysis investigating perinatal outcome following blastocyst- vs cleavage-stage embryo transfer, two multicenter studies on cytomegalovirus infection in pregnancy, and a follow-up study of a multicenter trial, which is the first to report on the long-term mortality and morbidity of cases receiving transplacental treatment for fetal supraventricular tachyarrhythmia. This issue also includes the newly updated ISUOG Practice Guideline on the performance of first-trimester ultrasound scan.

The November issue of Ultrasound in Obstetrics & Gynecology includes a systematic review and meta-analysis collating evidence on the performance of magnetic resonance imaging and ultrasound in detecting cervical and deep myometrial invasion in endometrial cancer, a multicenter study reporting on the incidence, clinical features and perinatal outcome of anomalous fetuses with late-onset growth restriction, and two studies on open spina bifida, focusing on prenatal treatment and the relationship between white matter development and motor deficits in the affected cases.

The October issue of Ultrasound in Obstetrics & Gynecology includes a systematic review and meta-analysis providing the most up-to-date evidence on the performance of the sliding sign for detecting pouch of Douglas obliteration and bowel involvement in patients with endometriosis, the first study to investigate the diagnostic yield of whole-genome sequencing for non-immune hydrops fetalis, a study investigating the optimal method for selective fetal reduction in complicated monochorionic pregnancies, and a study evaluating the diagnostic test accuracy of magnetic resonance imaging and pelvic floor ultrasound for diagnosis of levator ani muscle avulsion. Additionally, the October issue features the latest research on the impact of pre-eclampsia on the maternal brain, including its detrimental effects on functional organization of the brain and integrity of the blood–brain barrier, detectable years after the complicated pregnancy.

The September issue of Ultrasound in Obstetrics & Gynecology includes a systematic review and meta-analysis presenting unexpected findings regarding the relationship between severe smallness and perinatal outcome, a State-of-the-Art Review that collates the most up-to-date evidence on diagnostic tools for endometriosis, and a multicenter, prospective study demonstrating the value of third-trimester ultrasound for diagnosing clinically significant placenta accreta spectrum disorders. Additionally, the new issue features two novel studies on North American populations and an accompanying Editorial shedding light on the sociodemographic barriers to prenatal detection of congenital heart disease and their impact on women’s reproductive choices and perinatal outcome.

The August issue of Ultrasound in Obstetrics & Gynecology includes a multicenter study developing and validating radiomics models to predict high-risk endometrial cancer, a prospective study providing insight into ultrasound features observed in asymptomatic women with endometrial pathology, and a systematic review and meta-analysis investigating the true incidence and outcomes of brain abnormality in surviving children following laser surgery for twin-to-twin transfusion syndrome. The August issue also features two novel studies providing complementary evidence supporting the role of uteroplacental dysfunction in preterm birth and discussing the potential of placental biomarkers in the prediction of preterm delivery in the first trimester. This month also sees the release of an Early View version of ISUOG Practice Guidelines on the role of ultrasound in the prediction of spontaneous preterm birth.

The July issue of Ultrasound in Obstetrics & Gynecology includes a systematic review and meta-analysis evaluating perinatal outcome of triplet pregnancies following fetoscopic laser surgery for twin–twin transfusion syndrome, a new study exploring the role of ophthalmic artery Doppler in the prediction of pregnancy complications, a prospective study comparing fetal growth in IVF/ICSI pregnancies following frozen–thawed vs fresh blastocyst transfer and a Delphi study providing revised definitions of the MUSA features of adenomyosis. This issue also includes an Opinion providing an overview of our current understanding of monkeypox infection in pregnancy and recommendations for the management of suspected or confirmed cases.

To mark Pre-eclampsia Awareness Month, the May issue of Ultrasound in Obstetrics & Gynecology includes a series of research papers investigating the impact of pre-eclampsia on maternal health and potential biomarkers of the disorder. The issue also includes a systematic review and a retrospective study on the outcome of patients with aortic stenosis following fetal aortic valvuloplasty, a prospective study evaluating genetic causes of skeletal system abnormalities and a study validating IOTA models and O-RADS tool for preoperative assessment of adnexal lesions in a North American population.

The March issue of Ultrasound in Obstetrics & Gynecology includes a study validating a novel artificial intelligence tool for detecting CNS abnormalities and a study evaluating fetal growth patterns in monochorionic twin pregnancies complicated by Type-III selective fetal growth restriction. To coincide with Endometriosis Awareness Month, this issue also features a large prospective multicenter study evaluating the accuracy of ultrasound for detection of ovarian and deep endometriosis using #Enzian classification. Also, look out for the recently accepted State-of-the-Art Review on the strengths and limitations of diagnostic tools for endometriosis by an international group of experts in the field of endometriosis research.

The February issue of Ultrasound in Obstetrics & Gynecology includes a systematic review evaluating the postnatal outcome of fetuses with a rare diagnosis of apparently isolated agenesis of the septum pellucidum, an intriguing study assessing the risk of miscarriage in twin pregnancy following chorionic villus sampling using a statistical approach that simulates a RCT and a new study on COVID-19, investigating predictors of adverse outcome in affected pregnancies. The issue also includes the first prospective study to compare ultrasound, CT and a novel technique, whole-body diffusion-weighted MRI, for preoperative assessment of advanced ovarian cancer and an updated meta-analysis on the efficacy of vaginal progesterone for the prevention of adverse outcome in women with twin pregnancy and a short cervix.

The December issue of Ultrasound in Obstetrics & Gynecology includes a State-of-the-Art Review discussing the rationale for fetoscopic repair of complex gastroschisis, a study demonstrating evidence of SARS-CoV-2 vertical transmission according to the WHO criteria, a study showing similar characteristics of ectopic pregnancies prior to vs during the COVID-19 pandemic and a study finding that transvaginal sonography determines accurately the extent of infiltration of rectosigmoid deep endometriosis. Also in the issue, find out who were the all-important contributors to UOG’s peer-review process in 2021.

The November issue of Ultrasound in Obstetrics & Gynecology includes a systematic review identifying perinatal risk factors for neurodevelopmental impairment after laser surgery for twin–twin transfusion syndrome, a study showing a reduction in the rate of preterm birth during COVID-19 pandemic restriction measures in Melbourne, Australia, a cost-effectiveness analysis demonstrating a reduction in disease prevalence and health-service costs associated with a model of first-trimester prediction and prevention of preterm pre-eclampsia, and a secondary analysis of a RCT finding no difference in psychological response to early miscarriage and treatment satisfaction after expectant management vs misoprostol treatment.

The October issue of Ultrasound in Obstetrics & Gynecology includes a mini-series of papers on first-trimester screening for pre-eclampsia, a prospective cohort study and meta-analysis demonstrating the substantial incremental yield of exome sequencing over CMA or karyotyping in fetal hydrops, a study confirming the benefit of valacyclovir administration from the first trimester for secondary prevention of congenital CMV infection, a study evaluating which maneuver for managing umbilical cord prolapse provides the greatest effect on fetal head elevation, a study demonstrating the anatomical features that prevent reliable assessment of endometrial thickness on transvaginal ultrasound, and a study showing that long-term neurological outcomes after percutaneous fetoscopic open spina bifida repair are similar to those after hysterotomy-assisted repair.

The September issue of Ultrasound in Obstetrics & Gynecology includes a study on the impact of crown–rump measurement error on assessment of fetal growth, a study on the safety and efficacy of the Pfizer/BioNTech COVID-19 vaccine in pregnant women, a study presenting reference ranges and calculators for fetal cardiac relative size and geometry parameters, and a study assessing the combination of the Proactive Molecular Risk Classifier for Endometrial cancer (ProMisE) with sonographic and demographic characteristics in the preoperative prediction of recurrence or progression of endometrial cancer.

The August issue of Ultrasound in Obstetrics & Gynecology includes an updated cohort study and meta-analysis on cell-free DNA testing in screening for trisomies in twins, a study longitudinally evaluating motor function in prenatally vs postnatally repaired open neural tube defect cases, a study on cervical electrical impedance spectroscopy to predict spontaneous preterm delivery in asymptomatic women, a study on the association between vaginal birth after Cesarean section and levator ani muscle avulsion, and newly updated ISUOG Practice Guidelines on the use of Doppler velocimetry in obstetrics.

The July issue of Ultrasound in Obstetrics & Gynecology includes a study on the risk of fetal loss after chorionic villus sampling in twin pregnancy, a study on the prenatal sonographic manifestation of esophageal atresia with or without tracheoesophageal fistula, a study on the effect of elective induction of labor at 39 weeks on children’s educational outcomes, and a Consensus Statement from ESGO/ISUOG/IOTA/ESGE on the preoperative diagnosis of ovarian tumors.

ISUOG along with ESGO, IOTA and ESGE have issued a Consensus Statement on the preoperative diagnosis of ovarian tumors. This joint publication presents clinically relevant and evidence-based statements on the diagnosis of these tumors and assessment of disease spread, including imaging techniques, biomarkers and predictive models.

The June issue of Ultrasound in Obstetrics & Gynecology includes a consensus opinion from the VITA group on terms, definitions and measurements to describe the sonographic features of lymph nodes, a debate on the relative merits of the SMFM and ISUOG guidelines for diagnosing and managing fetal growth restriction, a State-of-the-Art Review on controversies in the management of twin pregnancy, and a RCT on routine third-trimester ultrasound for the detection of small-for-gestational age in low-risk pregnancies.