Explore a chapter on Microcephaly and Megalencephaly.
Microcephaly
Microcephaly is the combination of a small head, and brain, with neurologic compromise. It is a heterogeneous malformation with multiple etiologies that include hereditary conditions with a high risk of recurrence. Abnormal cerebral development is frequently present.
Megalencephaly
Macrocephaly, enlarged head circumference (HC), is multifactorial and may result from hydrocephalus, cerebral edema, focal and pericerebral fluid collections, thickened calvarium, neoplasia and megalencephaly.