In 2009, the Hypertension and Preeclampsia Intervention Trial At near Term-I (HYPITAT- I) trial showed that inducing labor in women with gestational hypertension or preeclampsia at the end of pregnancy reduces the number of high risk situations for the mother, without compromising the health of newborns. A new analysis evaluated the impact of the HYPITAT-I findings on timing of labor and subsequent outcomes for mother and child in the Netherlands.
As the prevalence of maternal and fetal complications increases with advancing pregnancy beyond 39 weeks, induction of labor at 39 weeks has been proposed as a means to ensure optimal maternal and newborn health. An Ultrasound in Obstetrics & Gynecology analysis of data from five randomized controlled trials found that elective induction of labor in uncomplicated singleton pregnancy from 39 weeks’ gestation is not associated with higher rates of complications and, in fact, may reduce the risk of cesarean section, hypertensive disease of pregnancy, and need for respiratory support in newborns.
“We now have enough data from uncomplicated singleton pregnancies to support the finding that induction of labor from 39 weeks' gestation seems a safe and potentially beneficial option for women,” said lead author Dr. Alexandros Sotiriadis, of the Aristotle University of Thessaloniki, in Greece. “Before undertaking induction of labor in low-risk pregnancies, women need to be aware that it can lead to a more prolonged and painful process than spontaneous labor. Maternity services will also need to consider the impact of widespread labor induction on staffing and capacity of labor wards.”
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