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Read the newly updated ISUOG Practice Guidelines on the performance of fetal MRI.

The February issue of Ultrasound in Obstetrics & Gynecology includes a systematic review and meta-analysis investigating neonatal and long-term outcomes of pregnancies with cytomegalovirus infection and negative amniocentesis, a national cohort study exploring the association of cerebral palsy with placental and umbilical cord disorders, and a systematic review of studies reporting on maternal and perinatal outcomes of pregnancies complicated by poxvirus infections, including monkeypox. Also in the issue are a new study from the IOTA collaboration describing a novel strategy allowing to reliably discriminate between benign and malignant ovarian tumors and an accompanying Editorial on the topic by Prof. Davor Jurkovic. Finally, the February issue includes the newly updated ISUOG Practice Guideline on the performance of fetal magnetic resonance imaging.

This document aims to provide guidance for healthcare practitioners performing, or planning to perform, pregnancy scans at 11 + 0 to 14 + 0 weeks.

The January issue of Ultrasound in Obstetrics & Gynecology includes a systematic review and meta-analysis investigating perinatal outcome following blastocyst- vs cleavage-stage embryo transfer, two multicenter studies on cytomegalovirus infection in pregnancy, and a follow-up study of a multicenter trial, which is the first to report on the long-term mortality and morbidity of cases receiving transplacental treatment for fetal supraventricular tachyarrhythmia. This issue also includes the newly updated ISUOG Practice Guideline on the performance of first-trimester ultrasound scan.

The December issue of Ultrasound in Obstetrics & Gynecology includes a prospective study investigating the utility of a machine-learning-based model for predicting pre-eclampsia, two studies on anal sphincter trauma and a study comparing fetal and neonatal sonographic parameters of brain ventricular size. Also in the issue are the first systematic review and meta-analysis to report on the incidence of congenital heart disease in fetuses with premature atrial contractions and an accompanying Editorial by Julene Carvalho proposing a systematic management protocol for cases with rhythm irregularities.

ISUOG's Visual Encyclopedia (VISUOG) chapter on Cervical Teratomas is open access this December. This month we have a discount code to become an ISUOG member and view VISUOG for an entire year.

The November issue of Ultrasound in Obstetrics & Gynecology includes a systematic review and meta-analysis collating evidence on the performance of magnetic resonance imaging and ultrasound in detecting cervical and deep myometrial invasion in endometrial cancer, a multicenter study reporting on the incidence, clinical features and perinatal outcome of anomalous fetuses with late-onset growth restriction, and two studies on open spina bifida, focusing on prenatal treatment and the relationship between white matter development and motor deficits in the affected cases.

The October issue of Ultrasound in Obstetrics & Gynecology includes a systematic review and meta-analysis providing the most up-to-date evidence on the performance of the sliding sign for detecting pouch of Douglas obliteration and bowel involvement in patients with endometriosis, the first study to investigate the diagnostic yield of whole-genome sequencing for non-immune hydrops fetalis, a study investigating the optimal method for selective fetal reduction in complicated monochorionic pregnancies, and a study evaluating the diagnostic test accuracy of magnetic resonance imaging and pelvic floor ultrasound for diagnosis of levator ani muscle avulsion. Additionally, the October issue features the latest research on the impact of pre-eclampsia on the maternal brain, including its detrimental effects on functional organization of the brain and integrity of the blood–brain barrier, detectable years after the complicated pregnancy.

The September issue of Ultrasound in Obstetrics & Gynecology includes a systematic review and meta-analysis presenting unexpected findings regarding the relationship between severe smallness and perinatal outcome, a State-of-the-Art Review that collates the most up-to-date evidence on diagnostic tools for endometriosis, and a multicenter, prospective study demonstrating the value of third-trimester ultrasound for diagnosing clinically significant placenta accreta spectrum disorders. Additionally, the new issue features two novel studies on North American populations and an accompanying Editorial shedding light on the sociodemographic barriers to prenatal detection of congenital heart disease and their impact on women’s reproductive choices and perinatal outcome.

The August issue of Ultrasound in Obstetrics & Gynecology includes a multicenter study developing and validating radiomics models to predict high-risk endometrial cancer, a prospective study providing insight into ultrasound features observed in asymptomatic women with endometrial pathology, and a systematic review and meta-analysis investigating the true incidence and outcomes of brain abnormality in surviving children following laser surgery for twin-to-twin transfusion syndrome. The August issue also features two novel studies providing complementary evidence supporting the role of uteroplacental dysfunction in preterm birth and discussing the potential of placental biomarkers in the prediction of preterm delivery in the first trimester. This month also sees the release of an Early View version of ISUOG Practice Guidelines on the role of ultrasound in the prediction of spontaneous preterm birth.

The scope of this Guideline is to evaluate the role of ultrasound in the prediction of preterm birth in asymptomatic women and women with symptoms of preterm labor, with the goal of preventing prematurity and improving the perinatal and long-term outcome of the infant.

The July issue of Ultrasound in Obstetrics & Gynecology includes a systematic review and meta-analysis evaluating perinatal outcome of triplet pregnancies following fetoscopic laser surgery for twin–twin transfusion syndrome, a new study exploring the role of ophthalmic artery Doppler in the prediction of pregnancy complications, a prospective study comparing fetal growth in IVF/ICSI pregnancies following frozen–thawed vs fresh blastocyst transfer and a Delphi study providing revised definitions of the MUSA features of adenomyosis. This issue also includes an Opinion providing an overview of our current understanding of monkeypox infection in pregnancy and recommendations for the management of suspected or confirmed cases.

Read the newly updated ISUOG Practice Guidelines on how to perform the routine mid-trimester fetal ultrasound scan.

The June issue of Ultrasound in Obstetrics & Gynecology includes a systematic review and meta-analysis evaluating the diagnostic performance of exome sequencing in fetuses with multisystem malformations, a comprehensive study evaluating the cost-effectiveness of strategies for prevention of preterm birth and a study presenting a new algorithm for stratification of monochorionic twin pregnancies with Type-III sFGR according to fetal death risk. Also in the issue are a nationwide study on postnatal outcome of late-preterm twins in South Korea and an accompanying Editorial on the optimal timing of delivery in twin pregnancies. Finally, in this issue, look out for the newly updated ISUOG Guidelines for the performance of the routine mid-trimester fetal scan and an Opinion providing recommendations for fetal cardiac imaging in patients with degraded acoustic windows.

To mark Pre-eclampsia Awareness Month, the May issue of Ultrasound in Obstetrics & Gynecology includes a series of research papers investigating the impact of pre-eclampsia on maternal health and potential biomarkers of the disorder. The issue also includes a systematic review and a retrospective study on the outcome of patients with aortic stenosis following fetal aortic valvuloplasty, a prospective study evaluating genetic causes of skeletal system abnormalities and a study validating IOTA models and O-RADS tool for preoperative assessment of adnexal lesions in a North American population.

The March issue of Ultrasound in Obstetrics & Gynecology includes a study validating a novel artificial intelligence tool for detecting CNS abnormalities and a study evaluating fetal growth patterns in monochorionic twin pregnancies complicated by Type-III selective fetal growth restriction. To coincide with Endometriosis Awareness Month, this issue also features a large prospective multicenter study evaluating the accuracy of ultrasound for detection of ovarian and deep endometriosis using #Enzian classification. Also, look out for the recently accepted State-of-the-Art Review on the strengths and limitations of diagnostic tools for endometriosis by an international group of experts in the field of endometriosis research.

The February issue of Ultrasound in Obstetrics & Gynecology includes a systematic review evaluating the postnatal outcome of fetuses with a rare diagnosis of apparently isolated agenesis of the septum pellucidum, an intriguing study assessing the risk of miscarriage in twin pregnancy following chorionic villus sampling using a statistical approach that simulates a RCT and a new study on COVID-19, investigating predictors of adverse outcome in affected pregnancies. The issue also includes the first prospective study to compare ultrasound, CT and a novel technique, whole-body diffusion-weighted MRI, for preoperative assessment of advanced ovarian cancer and an updated meta-analysis on the efficacy of vaginal progesterone for the prevention of adverse outcome in women with twin pregnancy and a short cervix.

The January issue of Ultrasound in Obstetrics & Gynecology is completely free to read! The issue includes a systematic review evaluating the diagnostic accuracy of first-trimester ultrasound examination in the detection of fetal cardiac abnormalities, a study reporting on clinical experience with non-invasive prenatal screening for single-gene disorders, a study developing and validating a model for prediction of placental dysfunction-related stillbirth from maternal factors, fetal weight and uterine artery Doppler at mid-gestation, an analysis of 13,062 SARS-CoV-2-positive pregnancies evaluating comorbidities and social vulnerability as risk factors of maternal death in Mexico, and a prospective study assessing first-trimester screening for placenta accreta spectrum in women with prior Cesarean delivery using transvaginal ultrasound assessment of the lower uterine segment scar.

The October issue of Ultrasound in Obstetrics & Gynecology includes a mini-series of papers on first-trimester screening for pre-eclampsia, a prospective cohort study and meta-analysis demonstrating the substantial incremental yield of exome sequencing over CMA or karyotyping in fetal hydrops, a study confirming the benefit of valacyclovir administration from the first trimester for secondary prevention of congenital CMV infection, a study evaluating which maneuver for managing umbilical cord prolapse provides the greatest effect on fetal head elevation, a study demonstrating the anatomical features that prevent reliable assessment of endometrial thickness on transvaginal ultrasound, and a study showing that long-term neurological outcomes after percutaneous fetoscopic open spina bifida repair are similar to those after hysterotomy-assisted repair.

The August issue of Ultrasound in Obstetrics & Gynecology includes an updated cohort study and meta-analysis on cell-free DNA testing in screening for trisomies in twins, a study longitudinally evaluating motor function in prenatally vs postnatally repaired open neural tube defect cases, a study on cervical electrical impedance spectroscopy to predict spontaneous preterm delivery in asymptomatic women, a study on the association between vaginal birth after Cesarean section and levator ani muscle avulsion, and newly updated ISUOG Practice Guidelines on the use of Doppler velocimetry in obstetrics.