This leaflet is to help you understand what an ovarian carcinosarcoma is, what tests you need and the implication of being diagnosed are for you, your baby and your family.

What is an ovarian Carcinosarcoma?

Ovarian carcinosarcomas, also known as mixed malignant Müllerian tumors, are rare types of malignant ovarian tumors. These neoplasms are typically diagnosed in postmenopausal women and are often bilateral. It is a rare condition and accounts for 1–4% of all ovarian malignant tumors.

What are the clinical symptoms? 

The most frequent clinical symptoms are abdominal or pelvic pain, abdominal bloating and distension, and gastrointestinal complaints related to the rapid tumor growth and palpable abdominal mass. 

Should I have more tests done?

It could be useful to do a blood test to check a serum marker called Ca 125, because it is usually high. A transvaginal and transabdominal ultrasound evaluation could be useful as first imaging examination to make the diagnosis. Then, a total body Computed Tomography scan is usually recommended to identify any signs of tumor spread before surgery.

What is the best treatment?

Surgery followed by chemotherapy is the standard treatment.

What is the prognosis? Will it happen again?

Unfortunately, the prognosis is poor, and most patients relapse within one year after completion of treatment.

What other questions should I ask?

  • Is the tumor limited to my ovary or is it advanced?
  • What is the best treatment for my condition?
  • Will I be able to get pregnant after treatment? 
  • What are the problems that can happen with the treatment?
  • Where is the best center for me to receive treatments?
  • Which follow-up will I need after treatment? 

Last updated: August 2022